Dr. Kim is the P. Michael Conneally Professor of Medical and Molecular Genetics. Dr. Kim graduated Summa Cum Laude in 2000 from Pohang University of Science & Technology in Korea with a bachelor’s degree in life science. He earned his Ph.D. from Mayo Clinic College of Medicine in 2007 under the guidance of Dr. Todd Golde and completed his postdoctoral training at Washington University in the laboratory of Dr. David Holtzman. After 3 years of postdoctoral training, he established his laboratory at Washington University, as an Assistant Professor in the Department of Neurology. In June 2013, Dr. Kim joined the Department of Neuroscience at Mayo Clinic. After 5 years of tenure as a Senior Associate Consultant I at Mayo Clinic, Dr. Kim relocated his laboratory to the Stark Neurosciences Research Institute at IU School of Medicine in 2018.
Dr. Kim’s laboratory is interested in understanding the molecular and cellular basis of neuronal and glial dysfunction in Alzheimer’s disease, other aging-associated neurodegenerative diseases, and normal brain aging. Research in our lab is aimed at developing therapeutic strategies for Alzheimer’s disease by targeting brain lipid-regulating proteins, such as apolipoprotein E (ApoE), low density lipoprotein receptor (LDLR), and ATP-binding cassette transporter A1 (ABCA1). We are also interested in the role of epigenetics and non-coding RNAs in the pathogenesis of Alzheimer’s disease and other aging-associated neurodegenerative diseases. Emerging transcriptomics technologies recently revealed that many non-coding regions actually encode functional RNAs, such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs). Using cell culture, animal models, and systems biology approaches, we study non-coding RNAs that may play critical roles in neurodegenerative diseases, brain aging and cardiovascular diseases.